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Effects of SET2 ( i.p. 25 mg/kg) on heart electrophysiology and blood pressure. a. Heart rate. b-g. Electrocardiography parameters (RR interval, PR interval, QRS complex, QT interval, QTc, ST height). h. Systolic blood pressure. i. Representative ECG recordings – Control vs. SET2 group at 2 and 120 min since administration. All measurements were assesed at 2 min and 120 min after SET2/vehicle administration according to the experimental group. Data are presented as mean ± SEM.

Journal: Scientific Reports

Article Title: Pharmacokinetic analysis of selective TRPV2 inhibitor SET2 in rats

doi: 10.1038/s41598-025-13891-7

Figure Lengend Snippet: Effects of SET2 ( i.p. 25 mg/kg) on heart electrophysiology and blood pressure. a. Heart rate. b-g. Electrocardiography parameters (RR interval, PR interval, QRS complex, QT interval, QTc, ST height). h. Systolic blood pressure. i. Representative ECG recordings – Control vs. SET2 group at 2 and 120 min since administration. All measurements were assesed at 2 min and 120 min after SET2/vehicle administration according to the experimental group. Data are presented as mean ± SEM.

Article Snippet: Electrocardiographic (ECG) and systolic blood pressure (BP) recordings were obtained as part of a single protocol using the ADInstruments setup and analysed with LabChart 8 software (ADInstruments, Dunedin, New Zealand).

Techniques: Control